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The virus interacts with the components and receptors of lipoproteins, which may lead to its development.

HSV asymptomatic shedding occurs at some time in most individuals infected with herpes.Herpetic keratoconjunctivitis, a primary infection, typically presents as swelling of the conjunctiva and eyelids (blepharoconjunctivitis), accompanied by small white itchy lesions on the surface of the cornea.Herpetic sycosis is a recurrent or initial herpes simplex infection affecting primarily the hair follicle.Symptoms may include painful swallowing (odynophagia) and difficulty swallowing (dysphagia).

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It is often associated with impaired immune function (e.g.During immunodeficiency, herpes simplex can cause unusual lesions in the skin.

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